insane: INsulin Secretion ANalysEr

A user-friendly interface, using Shiny, to analyse glucose-stimulated insulin secretion (GSIS) assays in pancreatic beta cells or islets. The package allows the user to import several sets of experiments from different spreadsheets and to perform subsequent steps: summarise in a tidy format, visualise data quality and compare experimental conditions without omitting to account for technical confounders such as the date of the experiment or the technician. Together, insane is a comprehensive method that optimises pre-processing and analyses of GSIS experiments in a friendly-user interface. The Shiny App was initially designed for EndoC-betaH1 cell line following method described in Ndiaye et al., 2017 (<doi:10.1016/j.molmet.2017.03.011>).

Version: 1.0.3
Depends: R (≥ 3.6.0)
Imports: stats, utils, broom (≥ 0.5.6), dplyr (≥ 1.0.0), DT (≥ 0.13), ggplot2 (≥ 3.3.2), ggpubr (≥ 0.3.0), glue (≥ 1.4.1), patchwork (≥ 1.0.1), purrr (≥ 0.3.4), readxl (≥ 1.3.1), shiny (≥ 1.5.0), tidyr (≥ 1.1.0)
Suggests: covr (≥ 3.5.0), roxygen2 (≥ 7.1.0), knitr (≥ 1.29), testthat (≥ 2.3.2), rmarkdown (≥ 2.3)
Published: 2023-11-14
DOI: 10.32614/CRAN.package.insane
Author: Mickaël Canouil ORCID iD [aut, cre]
Maintainer: Mickaël Canouil <pro at>
License: MIT + file LICENSE
NeedsCompilation: no
Materials: README NEWS
CRAN checks: insane results


Reference manual: insane.pdf
Vignettes: insane: INsulin Secretion ANalysEr
insane: Experimental Protocol


Package source: insane_1.0.3.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): insane_1.0.3.tgz, r-oldrel (arm64): insane_1.0.3.tgz, r-release (x86_64): insane_1.0.3.tgz, r-oldrel (x86_64): insane_1.0.3.tgz
Old sources: insane archive


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